World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : the Mitochondrion-like Organelle of Trimastix Pyriformis Contains the Complete Glycine Cleavage System, Volume 7

By Saks, Valdur

Click here to view

Book Id: WPLBN0003961252
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : the Mitochondrion-like Organelle of Trimastix Pyriformis Contains the Complete Glycine Cleavage System, Volume 7  
Author: Saks, Valdur
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Saks, V. (n.d.). Plos One : the Mitochondrion-like Organelle of Trimastix Pyriformis Contains the Complete Glycine Cleavage System, Volume 7. Retrieved from http://www.nationalpubliclibrary.info/


Description
Description : All eukaryotic organisms contain mitochondria or organelles that evolved from the same endosymbiotic event like classical mitochondria. Organisms inhabiting low oxygen environments often contain mitochondrial derivates known as hydrogenosomes, mitosomes or neutrally as mitochondrion-like organelles. The detailed investigation has shown unexpected evolutionary plasticity in the biochemistry and protein composition of these organelles in various protists. We investigated the mitochondrion-like organelle in Trimastix pyriformis, a free-living member of one of the three lineages of anaerobic group Metamonada. Using 454 sequencing we have obtained 7 037 contigs from its transcriptome and on the basis of sequence homology and presence of N-terminal extensions we have selected contigs coding for proteins that putatively function in the organelle. Together with the results of a previous transcriptome survey, the list now consists of 23 proteins – mostly enzymes involved in amino acid metabolism, transporters and maturases of proteins and transporters of metabolites. We have no evidence of the production of ATP in the mitochondrion-like organelle of Trimastix but we have obtained experimental evidence for the presence of enzymes of the glycine cleavage system (GCS), which is part of amino acid metabolism. Using homologous antibody we have shown that H-protein of GCS localizes into vesicles in the cell of Trimastix. When overexpressed in yeast, H- and P-protein of GCS and cpn60 were transported into mitochondrion. In case of H-protein we have demonstrated that the first 16 amino acids are necessary for this transport. Glycine cleavage system is at the moment the only experimentally localized pathway in the mitochondrial derivate of Trimastix pyriformis.

 

Click To View

Additional Books


  • Plos One : Production of Lacz Inducible ... (by )
  • Plos One : Systematic Analysis of Experi... (by )
  • Plos One : Mitochondrial Dna Damage and ... (by )
  • Plos One : Influence of Non-alcoholic Fa... (by )
  • Plos One : Semidiurnal Temperature Chang... (by )
  • Plos One : Children’s and Adults’ On-lin... (by )
  • Plos One : Liver-specific Pgc-1Beta Defi... (by )
  • Plos One : Genetical Genomics Identifies... (by )
  • Plos One : Prosthetic Joint Infection in... (by )
  • Plos One : Experimental Adaptation of Wi... (by )
  • Plos One : Associations Between Apoe Gen... (by )
  • Plos One : Vegfr1 and Vegfr2 Involvement... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from National Public Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.